The purpose of this study is to investigate the differences in DNA that are associated with stress and how they may contribute to the cause of ASD. This research is being done because at this time no one knows how autism develops. We think that genes and stress may work together in the development of some cases of ASD. We will be looking at how stress and other environmental factors, including diet, interact with one’s genetic makeup. This study will include surveys and a blood draw.
The purpose of this study is to better understand the range of cognitive effects of propranolol in autism. We will test for effects of propranolol on verbal memory, working memory, spatial memory, attention, mood, and anxiety, and determine whether Galvanic skin response and heart rate variability predicts the degree of cognitive benefit.
The purpose of this study is to better understand the effects of propranolol on cognition (thinking) in those with ASD. Participants will attend 3 sessions at the MU Brain Imaging Center where they will take propranolol, nadolol, or placebo (sugar pill). Then, participants will be placed in an MRI machine where we will measure the effects of the drug on language, memory, problem solving, and connectivity in the brain. Furthermore, we will determine whether Galvanic skin response (i.e. level of skin sweat) and heart rate variability predict the degree of benefit from propranolol.
This study is being conducted as children with autism are frequently affected by gastrointestinal (GI) problems. The purpose of this study is to examine the relationship between GI symptoms and stress in autism.
The purpose of this study is to learn more about how people with and without autism react to different types of screen-based media, such as video games. Participants will be asked to complete two brief problem-solving tasks, interact with screen-based media, such as video games, and fill out a few short questionnaires. The visit should take approximately 1 ½ to 2 hours.