University of Missouri
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Columbia, MO 65211



SPARK is a free online study with a simple mission: to speed up research and advance the understanding of autism. By building a community of tens of thousands of individuals with autism and their biological family members who provide behavioral and genetic data, SPARK will be the largest autism research study to date.

Participation in SPARK can be done entirely at home — register online here.

Find out more about what’s involved on our SPARK page.

Questions? Contact Amanda Shocklee at 573-884-6092 or


Evaluation of Pupillary Light Reflex in Infants

The purpose of this study is to test the theory that dynamic pupillary light reflex (PLR- the temporary constriction of the pupil in response to a brief burst of light) can be used as a noninvasive tool for early identification of autism or other developmental disorders. PLR is a measure of how the pupil reacts to light.  This research is being done because currently there is no simple instrument can detect autism and many other developmental disorders in young children.


Targeting Sleep in Kids with Autism Spectrum Disorders

The purpose of the study is to test a new family-based behavioral sleep intervention designed to target sleep problems in children with Autism Spectrum Disorders (ASD).