University of Missouri
205 Portland Street
Columbia, MO 65211



SPARK is a free online study with a simple mission: to speed up research and advance the understanding of autism. By building a community of tens of thousands of individuals with autism and their biological family members who provide behavioral and genetic data, SPARK will be the largest autism research study to date.

Participation in SPARK can be done entirely at home — register online here.

Find out more about what’s involved on our SPARK page.

Questions? Contact Samantha Hunter at 573-882-6479 or


The purpose of this study is to validate the ability of a remote eye gaze tracker to differentiate children diagnosed with Autism Spectrum Disorder (ASD) to those with developmental delays. We will also be looking at how well eye gaze correlates with autism symptom severity and language ability.

REACH App Study

The purpose of this study is to test the effectiveness of an iPhone-based screening tool for identifying children with autism.

Brain Imaging Study

The purpose of the study is to develop a multimodal brain imaging platform to target precision medicine in autism and to further understand the role of neurotransmitters (GABA, dopamine, and glutamate) in brain function.  

Effect of transcutaneous vagal nerve stimulation on anxiety

The purpose of this study is to learn how anxiety in individuals with autism is affected by use of a device that stimulates the vagal nerve through a technique called transcutaneous vagal nerve stimulation (tVNS).


The purpose of this study is to develop better services for people with Down syndrome (DS) to manage their health.

Clinical Trial for Social Communication

The purpose of this clinical trial is to explore the effects on social communication in adolescents and young adults 12-21 years old with autism spectrum disorder.